1. Li PK, Chow KM, Cho Y , Fan S, Figueiredo AE, Harris T , et al. ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment. Perit Dial Int 2022; 42(2): 110-53. doi: 10.1177/08968608221080586 2. Brown MC, Simpson K, Kerssens JJ, Mactier RA; Scot tish Renal Registry. Peritoneal dialysis-associated peritonitis rates and outcomes in a national cohort are not improving in the postmillennium (2000-2007). Perit Dial Int 2011; 31(6): 639-50. doi: 10.3747/pdi.2010.00185 3. Boudville N, Kemp A, Clayton P, Lim W, Badve SV , Hawley CM, et al. Recent peritonitis associates with mortality among patients treated with peritoneal dialysis. J Am Soc Nephrol 2012; 23(8): 1398-405. doi: 10.1681/ASN.2011121135 4. Prasad N, Gupta A. Fungal peritonitis in peritonea l dialysis patients. Perit Dial Int 2005; 25(3): 207-22. 5. dos Santos ACML, Hernandes RT, Montelli AC. et al. Clinical and microbiological factors predicting outcomes of nonfermenting gram-negative bacilli peritonitis in peritoneal dialysis. Sci Rep 2021; 11: 12248. https://doi.org/10.1038/s41598-021-91410-0 6. Li PK, Szeto CC, Piraino B, de Arteaga J, Fan S, Figueiredo AE , et al. ISPD Peritonitis Recommendations: 2016 Update on Prevention and Treatment. Perit Dial Int 2016; 36(5): 481-508.

doi: 10.3747/pdi.2016.00078 7. Al Sahlawi M, Bargman JM, Perl J. Peritoneal Dialysis-Associated Peritonitis: Suggestions for Management and Mistakes to Avoid. Kidney Med 2020; 2(4): 467-75. doi: 10.1016/j. xkme.2020.04.010 amase-producing gram-negative bacilli has been observed. 7 This requires adjusting empirical regimens and emphasizes the need for local microbiological monitoring. Initial empirical treatment should cover both gram-positive and gram-negative bacteria and be adjusted according to the antibiogram. The ISPD suggests the use of vancomycin or a first-generation cephalosporin plus a third-generation cephalosporin or an aminoglycoside as initial treatment. clinical prognosis. A detailed understanding of the microbiological aspects of peritoneal dialysis-associated peritonitis is essential for its proper management. Continuous monitoring of etiological patterns and local sensitivity is key to optimizing empirical therapy and preventing long-term complications.